$users = DB::table('MyTable')
->where('id', 'LIKE', '%MySearch%')
->or_where('firstname', 'LIKE', '%MySearch%')
->or_where('lastname', 'LIKE', '%MySearch%')
->or_where('email', 'LIKE', '%MySearch%')
->or_where('address', 'LIKE', '%MySearch%');
->get();